Achieving reliable early detection in newborn screening demands tools that blend precision, throughput, and adaptability. The moment when a heel-prick bloodspot becomes a life-saving insight hinges on technology. Enter Revvity’s QSight® 225 MD UHPLC-MS/MS Screening System—a compact, high-throughput workhorse engineered for streamlined newborn screening workflows.
Dual-Source Design: Flexibility Meets Multiplexing
QSight 225 MD incorporates dual-source technology (ESI/APCI), allowing seamless transitions between ionization methods without reconfiguration. Two independent probes empower true multiplexing—so labs can switch modes mid-run with no downtime.
Superior Sensitivity with StayClean™ & HSID™ Technology
The instrument features a StayClean™ self-cleaning ion source and Laminar Flow Ion Guide (HSID™), dramatically reducing contamination and maintenance while delivering consistent, ultra-sensitive results for years.
High Throughput, Minimal Interruptions
Built for scale, QSight 225 MD processes thousands of dried blood spot (DBS) samples daily. The modular column switcher allows seamless transitions between Tier 1 and Tier 2 testing without plumbing changes, enabling highly specific follow-up assays directly from the same sample.
Streamlined Workflow with Smart Software
The intuitive Simplicity™ 3Q MD software simplifies method setup, acquisition, quantification, and reporting in three easy steps—complete with remote diagnostics and real-time data visualization.
Advanced Clinical Application: Reduced False Positives
QSight 225 MD’s UHPLC separation allows differentiation of isobaric acylcarnitines (e.g., C5 isomers), significantly reducing false positives in metabolic disorder screening and streamlining reflex testing workflows.
How The Science Support Helps You Implement QSight 225 MD For Newborn Screening
At The Science Support, we don’t just deliver cutting-edge instruments—we ensure they deliver results from day one:
- Site Assessment & Custom Integration: We tailor system setups to fit existing workflows.
- Installation & Training: Full onboarding ensures your team leverages the system’s full capabilities.
- Ongoing Service & Support: Local maintenance, spare parts, and rapid troubleshooting.
- Method Adaptation & Workflow Design: From sample prep to result reporting, we’ll help you optimize QSight integration.
Real-World Impact
Our collaboration with the Neonatal Screening Directorate (EPPEN) at the Institute of Child Health (IMP) in Athens demonstrates how the QSight 225 MD system enhances newborn screening. Since installation, their lab has expanded screening to 29 additional metabolic disorders—empowering earlier diagnosis and expanding preventive care across Greece.
In Summary
QSight 225 MD stands out as a compact, high-performance UHPLC-MS/MS platform delivering sensitivity, throughput, and agility in newborn screening workflows. Paired with implementation by The Science Support, laboratories gain the confidence and precision required for next-generation diagnostics. Interested in integrating QSight 225 MD into your screening program? Contact our team at sales@thesciencesupport.com or visit www.thesciencesupport.com for tailored solutions.