Early detection saves lives — especially when it comes to newborn screening. As global health systems aim to identify serious congenital conditions before symptoms appear, laboratories play a critical role in providing fast, accurate, and reliable test results. With conditions like congenital hypothyroidism, phenylketonuria (PKU), and severe combined immunodeficiency (SCID) detectable within days of birth, every minute counts.
At The Science Support, we help clinical laboratories and public health organizations in Greece and beyond build more efficient newborn screening workflows with cutting-edge technologies from our trusted partner, Revvity.
Why Optimize the Newborn Screening Workflow?
Newborn screening programs must balance several key priorities:
- High-throughput processing to handle thousands of samples weekly
- Analytical precision for low-abundance biomarkers
- Regulatory compliance with evolving standards
- Minimal turnaround time from sample collection to reporting
- Scalability to expand screening panels as new conditions are added
To address these needs, Revvity’s integrated screening ecosystem offers a complete portfolio — from sample collection and preparation to mass spectrometry, immunoassay analyzers, data management, and software for result interpretation.
Step 1: Sample Collection and Pre-Analytical Processing
Newborn screening starts with a dried blood spot (DBS) sample, typically collected within 24–72 hours after birth. Ensuring consistency at this stage is critical to accurate downstream testing.
Revvity’s solutions include:
- Delfia Trio: Combines disk removing, washing, and dispensing into one instrument offering a streamlined workflow for manual DELFIA users.
- DBS Puncher Instrument: Automates accurate punching of DBS cards, ensuring uniform sample size and traceability
- Panthera Puncher 9 Instrument: The new generation dried sample punching device for automatically punching dry blood spot samples into microtitration plates.
- Trinest Incubator shaker: A high-quality solution for all well plate applications
- Specimen Gate® Software: Manages sample tracking, barcode scanning, and electronic data capture for pre-analytical quality assurance
Step 2: Biochemical and Molecular Screening
Once the sample is processed, screening for multiple conditions can be done simultaneously using advanced platforms.
For biochemical screening:
- QSight® 225 MD Screening System: A robust LC-MS/MS system optimized for high-throughput newborn screening, enabling multiplexed detection of amino acids, acylcarnitines, and more — all from a single DBS punch.
For molecular screening:
- Eonis™ Real-Time PCR System: Enables early detection of SCID and spinal muscular atrophy (SMA), two of the most critical disorders for which early intervention is essential.
Step 3: Data Analysis and Decision Support
Efficient data interpretation is key to timely clinical action. Revvity’s integrated software platforms streamline this process:
- EVOYA Platform: Offers the capability to automatically import test result data into the cloud and process it for interpretation, significantly reducing errors associated with manual data handling.
- OZ Telepathy™ NBS: Enhances efficiency by generating electronic lab orders (ELO) and sending them directly to laboratory information management systems (LIMS) using HL7 standards-based messaging.
Why Revvity and The Science Support?
Revvity is a global leader in newborn screening technologies, active in over 100 countries with more than 500 million babies screened. Through our collaboration, The Science Support delivers:
- Local access to Revvity’s screening solutions
- Full installation, training, and technical support
- Consulting for workflow optimization and scale-up
- Ongoing supply of kits, reagents, and consumables
Whether you’re launching a new screening program or upgrading your lab’s capabilities, we’ll help you build a future-proof workflow from sample to result.
Ready to enhance your newborn screening capabilities?
Reach out to our team at sales@thesciencesupport.com or explore our complete offering in preimplantation, non-invasive prenatal and neonatal testing here.